Up-regulation of NK cell CD54. Up-regulation of CD54 expression as measured by the percentage of CD54_bright NK cells (n = 12). (A) Dose response curves for different mAbs. Error bars indicate SEM. (B) EC₅₀ values for different mAbs. Up-regulation of surface CD54 occurred at lower mAb concentrations with AME-D. Horizontal lines represent the mean.