American Society of Hematology

Figure 1.

$Figure 1. Treatment of primary CLL samples with Nutlin-3a or F-ara-A causes dose- and time-dependent apoptosis, and their combination shows synergistic effects. Cells from 30 Nutlin-sensitive samples were incubated with the indicated concentrations of Nutlin-3a or F-ara-A, and the annexin V–positive fractions were measured by flow cytometry at 24 and 72 hours. Results are expressed as mean ± SEM.$

Treatment of primary CLL samples with Nutlin-3a or F-ara-A causes dose- and time-dependent apoptosis, and their combination shows synergistic effects. Cells from 30 Nutlin-sensitive samples were incubated with the indicated concentrations of Nutlin-3a or F-ara-A, and the annexin V–positive fractions were measured by flow cytometry at 24 and 72 hours. Results are expressed as mean ± SEM.

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