AChE-R, RACK1, and PKC ϵ expression in megakaryocytes. (A) BM smears were stained with May-Grünwald (A) and specific antibodies to detect AChE-R (B), RACK1 (C), and PKCϵ (D). Arrows indicate labeled cells. (E) Illustration of the putative interaction between the 3 proteins. (F) Population distributions of Mk-labeling intensities for AChE-R, RACK1, and PKCϵ. □ represent FVB/N, and , TgR mice BM-labeling intensities. Note the shift to the right, indicating increased levels of these 3 proteins in Mks from TgR as compared with FVB/N mice. n = 50 cells per test. ^*P < .01, Student t test.