Figure 1.
Figure 1. Wt-Flt3 collaborates with NUP98-HOXA10 to induce leukemia in mice. Kaplan-Meier survival curves of mice given transplants of 5-FU–treated bm transduced with Flt3, NUP98-HOXA10, or NUP98-HOXA10 and Flt3. The median survival time for mice given transplants of bm cells expressing NUP98-HOXA10 + Flt3 was 114 days. The log-rank test was used to confirm the statistical significance between the NUP98-HOXA10 and NUP98-HOXA10 + Flt3 curves (P = .02).

Wt-Flt3 collaborates with NUP98-HOXA10 to induce leukemia in mice. Kaplan-Meier survival curves of mice given transplants of 5-FU–treated bm transduced with Flt3, NUP98-HOXA10, or NUP98-HOXA10 and Flt3. The median survival time for mice given transplants of bm cells expressing NUP98-HOXA10 + Flt3 was 114 days. The log-rank test was used to confirm the statistical significance between the NUP98-HOXA10 and NUP98-HOXA10 + Flt3 curves (P = .02).

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