Figure 2.
Neutralizing antibody responses after immunization with VSV and VSV-G in imatinib-treated mice. Imatinib-treated (•) (low-25/25 and high-dose 50/100 regimen) and nontreated naive C57BL/6 mice (▪) were infected intravenously with 2 × 106 VSV pfu (A-B) or immunized intravenously with 20 μg VSV-G (C-D). Neutralizing antibody responses were determined 4, 8, 12, and 15 or 20 days later. Filled symbols represent total Ig, open symbols represent IgG. Results are given as the mean ± SEM of 3 to 5 mice per group.
