Figure 3.
![Figure 3. Ca2+-triggered exocytosis of serotonin in BMDCs. (A) [3H]5-HT release (% of control) from BMDCs in response to extracellular ATP (100 μM) and ionomycin (10 μM). Data are means ± SE (n = 3; *P < .05; **P < .01). (B) BMDCs with apposed 5-μm carbon-fiber electrode; scale bar represents 20 μm. (C) Amperometric spikes evoked by application of extracellular ATP (100 μM) in a cell preloaded with 5-HT. (D) Representative spikes are shown on an expanded time scale. (E) Distribution of spike amplitudes (2 pA bins) from a total of 336 single events taken from 37 cells.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/107/3/10.1182_blood-2005-07-2903/4/zh80030690010003.jpeg?Expires=1730501125&Signature=DDpOY9YZoUgHpFsRvCzR8d74-P8ynGG0zxIivXMGos690qcvMKrq~0XYZEWH9yZ17zkfXUJ9qN8SKX6oZLBY4Mf4EBMPISJemCWX0ldRzz7DtXDaT0iGlx-88xfcPT8vTAaTvJfm4Ys~DmK648mP6zI~JA2REx7~iBvAmBCgt7iPY2jCZsKYWoS0g1ZwYJ~KykuL7TBwj8xf9pCnVfrLd1Cxx9mdFt067QVvb1Eq9RQFxPB6UIMIaRhbyfxnUsQxv254dbTslvhsATH2sBB2AgFerIMsV2zmCNANQrzW~vYMmo82TyERtnHzuvw29es63X-z8HZasgalTcrcEOVqjw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Ca2+-triggered exocytosis of serotonin in BMDCs. (A) [3H]5-HT release (% of control) from BMDCs in response to extracellular ATP (100 μM) and ionomycin (10 μM). Data are means ± SE (n = 3; *P < .05; **P < .01). (B) BMDCs with apposed 5-μm carbon-fiber electrode; scale bar represents 20 μm. (C) Amperometric spikes evoked by application of extracellular ATP (100 μM) in a cell preloaded with 5-HT. (D) Representative spikes are shown on an expanded time scale. (E) Distribution of spike amplitudes (2 pA bins) from a total of 336 single events taken from 37 cells.
