Figure 4.
Shared TCR clonotype in antileukemic T-cell lines derived from BM cells and PBMCs. The carrier-heteroduplex analysis was performed as described in “PCR and carrier-heteroduplex analysis.” Carrier-heteroduplex analysis performed on LDA generated from PBMCs obtained after A-BMT (lines A) and BM cells (lines B) from patient 7 (A) and patient 8 (B). Asterisks indicate shared heteroduplex bands. (C) Shows carrier-heteroduplex analysis performed on LDA generated from PBMCs (lines A and B) and BM cells (lines C and D), respectively, before (lines A and C) and after (lines B and D) A-BMT from patient 12. Asterisks indicate shared clonotypes; arrowheads indicate 4 shared heteroduplex bands selected for further molecular characterization.

Shared TCR clonotype in antileukemic T-cell lines derived from BM cells and PBMCs. The carrier-heteroduplex analysis was performed as described in “PCR and carrier-heteroduplex analysis.” Carrier-heteroduplex analysis performed on LDA generated from PBMCs obtained after A-BMT (lines A) and BM cells (lines B) from patient 7 (A) and patient 8 (B). Asterisks indicate shared heteroduplex bands. (C) Shows carrier-heteroduplex analysis performed on LDA generated from PBMCs (lines A and B) and BM cells (lines C and D), respectively, before (lines A and C) and after (lines B and D) A-BMT from patient 12. Asterisks indicate shared clonotypes; arrowheads indicate 4 shared heteroduplex bands selected for further molecular characterization.

Close Modal

or Create an Account

Close Modal
Close Modal