CACs demonstrate angiogenic potential in vivo. CACs (400 000 cells) were infused intravenously into NOD/SCID β2M mice 24 hours after surgical induction of hind-limb ischemia (control, n = 5; CACs, n = 9). (A) Representative laser Doppler images at 14 days after surgery. (B) Perfusion in the ischemic hind limb relative to nonischemic hind limb was measured at the indicated time after surgery (*P < .001).