Figure 2.
Figure 2. Functional assay in patient myeloma cells. Patient samples with high ABCG2 and low ABCG2 mRNA (as measured by QPCR) were assayed for ABCG2 function. The high ABCG2 expresser effluxed topotecan more efficiently than the lower expresser. Efflux was shown to be ABCG2 specific by the addition of tryprostatin A.

Functional assay in patient myeloma cells. Patient samples with high ABCG2 and low ABCG2 mRNA (as measured by QPCR) were assayed for ABCG2 function. The high ABCG2 expresser effluxed topotecan more efficiently than the lower expresser. Efflux was shown to be ABCG2 specific by the addition of tryprostatin A.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal