Figure 4.
Figure 4. Selective rescue of MTAP+ T-ALL cell line from L-alanosine toxicity by EFA or MTA. CEM and MOLT-4 human T-ALL cell lines were treated with 40 μM L-alanosine in the presence of increasing concentrations of EFA or MTA. Cells were cultured for 72 hours and viable cells were quantified using an XTT colorimetric assay kit. ▴ indicates MOLT-4 + EFA; •, MOLT-4 + MTA; ▵, CEM + EFA; ○, CEM + MTA.

Selective rescue of MTAP+ T-ALL cell line from L-alanosine toxicity by EFA or MTA. CEM and MOLT-4 human T-ALL cell lines were treated with 40 μM L-alanosine in the presence of increasing concentrations of EFA or MTA. Cells were cultured for 72 hours and viable cells were quantified using an XTT colorimetric assay kit. ▴ indicates MOLT-4 + EFA; •, MOLT-4 + MTA; ▵, CEM + EFA; ○, CEM + MTA.

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