Figure 6.
![Figure 6. Effect of PI3K inhibitors on proliferation and BCR-induced early signaling in the WEHI-231 B-cell lymphoma cell line. (A) Effect of different PI3K inhibitors on proliferation of WEHI-231 cells. Proliferation was measured by [3H]-thymidine incorporation after a 48-hour culture. (B) Effect of PI3K inhibitors on early signaling induced by anti-IgM treament in WEHI-231 cells. Left panel: WEHI-231 cells were stimulated with anti-IgM for 5 minutes in the absence or presence of different PI3K inhibitors. Total-cell lysates were immunoblotted using the indicated antibodies. Right panel: WEHI-231 cells were stimulated with anti-IgM for the indicated time points with or without IC87114. Error bars indicate SD.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/107/2/10.1182_blood-2005-07-3041/4/zh80020689410006.jpeg?Expires=1724239656&Signature=iA2Ub755IPrwzacH7h9qXo~tJDmSTb3tSLG1xHv4DRLr9zPxd-eVJw-1eNzkHa7XLQSYeeWoItdFwBuoXCift6jyZWED0d81kxmp5oYMklVRPWPtna1Hkjxbql2ELrIiXeISugQ~QATql4ZiBVcnC9MjmsID1QgqYvbPr9kbMZhjY0B6NOlRXY~y2U4-7f-~pKen7fY4c5IaO9pbRO--moIk2lyUPAg-DacNO-9uyB6jNBP8ykVW8nLTlyD61wgRlEhzhlyYpbkFZ0pP5NCDEu23dXkKx-DbcvJgsXRXqJ2T905Vd3G7wzGsfKeJgPi9wYWvigDiWRPSJhhT95qwng__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of PI3K inhibitors on proliferation and BCR-induced early signaling in the WEHI-231 B-cell lymphoma cell line. (A) Effect of different PI3K inhibitors on proliferation of WEHI-231 cells. Proliferation was measured by [3H]-thymidine incorporation after a 48-hour culture. (B) Effect of PI3K inhibitors on early signaling induced by anti-IgM treament in WEHI-231 cells. Left panel: WEHI-231 cells were stimulated with anti-IgM for 5 minutes in the absence or presence of different PI3K inhibitors. Total-cell lysates were immunoblotted using the indicated antibodies. Right panel: WEHI-231 cells were stimulated with anti-IgM for the indicated time points with or without IC87114. Error bars indicate SD.
