Erythropoietic response to severe malarial anemia in semi-immune mice. (A) Correlation between peak reticulocyte levels and minimum Hb levels during SMA in semi-immune mice (n = 14). (B) Hb (▴ and ▵) and reticulocyte (• and ○) levels ± SEM in mice with SMA (▴ and •, n = 4) or nonmalarial PHZ-induced anemia (▵ and ○, n = 6). Mice were selected for equivalent levels of anemia and data are normalized to the day of peak anemia (day = 0). ^**P < .01; ^***P < .001.