Figure 4.
Figure 4. Inhibition of thrombin-induced aggregation and secretion by the Rho kinase inhibitor Y-27632. Platelets were stimulated with thrombin (0.5 U/mL) in the absence or presence of the integrin αIIbβ3 blocker RGDS (0.5 mM) and the Rho kinase inhibitor Y-27632 (20 μM). Representative tracings for change in light transmission (LT) and ATP secretion are shown.

Inhibition of thrombin-induced aggregation and secretion by the Rho kinase inhibitor Y-27632. Platelets were stimulated with thrombin (0.5 U/mL) in the absence or presence of the integrin αIIbβ3 blocker RGDS (0.5 mM) and the Rho kinase inhibitor Y-27632 (20 μM). Representative tracings for change in light transmission (LT) and ATP secretion are shown.

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