Platelet depletion does not alter hematocrit. C57BL/6J mice were treated with CTL-Ig (□) or αPLT-Ig (▪) and killed 72 hours later. Anticoagulated whole blood was collected by cardiac puncture, and platelet numbers (A) and hematocrit (B) were determined (mean ± SEM). Data were analyzed using the Mann-Whitney test. Differences were considered significant when *P < .05.