Fig. 7.
Fig. 7. Survival after leukemia induction. / Total body irradiated B6 mice received 5 × 106 TCD BM and 2 × 106 splenic T cells from either allogeneic control (○, n = 10) and IL-18–pretreated (●, n = 10) BALB/c donors or syngeneic control (▵, n = 10) and IL-18–pretreated (▴, n = 10) B6 Ly5.2 donors. All the recipient mice were injected intravenously with 2000 EL4 tumor cells on day 0 (○ vs ●; **P < .01, and ▴ vs ●;P < .001).

Survival after leukemia induction.

Total body irradiated B6 mice received 5 × 106 TCD BM and 2 × 106 splenic T cells from either allogeneic control (○, n = 10) and IL-18–pretreated (●, n = 10) BALB/c donors or syngeneic control (▵, n = 10) and IL-18–pretreated (▴, n = 10) B6 Ly5.2 donors. All the recipient mice were injected intravenously with 2000 EL4 tumor cells on day 0 (○ vs ●; **P < .01, and ▴ vs ●;P < .001).

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