Fig. 3.
![Fig. 3. IL-2 reversed the T-cell tolerance to platelet Ags induced by CTLA4-Ig and/or CsA. / Following the same procedure for primary culture as that described in Figure 2, the T cells from 16 patients rendered tolerant to platelet Ags by CTLA4-Ig and/or CsA were rechallenged with platelet Ags and APCs in the presence (▪) or the absence (■) of IL-2 (10 U/mL) in the secondary culture. Proliferation was determined by [3H]thymidine incorporation on day 4 and shown as mean ± SD cpm.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/7/10.1182_blood-2002-06-1666/3/h80734058003.jpeg?Expires=1724137422&Signature=dUT27BTl7UL6XT-mV4CLPS2otmKytJ~lJTh7KSpvQvmnVZEcVjis3nyJqz30~8E8EDNKrN1tkJdyHMTGK3i0-aNZcKqHfiXNdnp7uTNbJYR-xjvjStPpRByWBSCMcBZTapf4srCH7gthx~ODTq8KOrcIGur3y9XJu3KaNAWGwcHv0-w60mBS5pM3sOq-W~fB~ZCyNyZhS8XU0fS8i6oDbso8FlBLoeLxERmPosVrQYW5mQs7cF8ZxMRfD-xJah6agEJIVED9wROh5oPLCzN-73DT~bbddJXKm0KPEQceX5-h1yrZxmcSlW3YpChNggZdeh7gWNRBEcWxcm4ccllPug__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
IL-2 reversed the T-cell tolerance to platelet Ags induced by CTLA4-Ig and/or CsA.
Following the same procedure for primary culture as that described in Figure 2, the T cells from 16 patients rendered tolerant to platelet Ags by CTLA4-Ig and/or CsA were rechallenged with platelet Ags and APCs in the presence (▪) or the absence (■) of IL-2 (10 U/mL) in the secondary culture. Proliferation was determined by [3H]thymidine incorporation on day 4 and shown as mean ± SD cpm.
