Secretion of basic fibroblast growth factor (bFGF) by myeloma cells.

Basal bFGF concentrations were determined in supernatants of myeloma cell lines (RPMI-8226, U-266, OPM-2, KMS-11, KMS-18; n = 8 independent experiments performed in triplicates per cell line) and of purified CD38^high/CD138⁺ marrow myeloma cells from patients (MM, n = 18; see also Figure 4) after 72 hours of culture. Basic FGF concentrations were corrected for 10⁶cells. Data are presented as medians and interquartile ranges.