Platelets in mice that received bone marrow transplants were of donor genotype.

Platelets isolated from the mice receiving transplants were activated by thrombin, incubated with FITC-labeled anti P-selectin antibodies, and analyzed by flow cytometry. A representative histogram for each set of chimeric animals is shown; ko-wt (A), wt-ko (B). The shaded curve represents P-selectin expression on activated platelets from an animal receiving a bone marrow transplant, whereas the nonshaded curve was obtained by staining activated platelets of a control mouse without transplant of the same genotype as the recipient.