Targeted entry into CHO-CD38 cells.

(A) Only the MV-αCD38 virus and not MV-αCEA or MV-Edm was able to enter and infect CHO-CD38 cells. Infection was reduced if the MV-αCD38 virions were treated with FXa protease to remove the scFv. (B) All 3 viruses were fully infectious on Vero cells, and infectivities were not significantly affected by protease treatment.