Fig. 1.
Activation of intracellular signaling pathways in HDMECs via CD36.
The intracellular signaling pathways in HDMECs were activated via CD36 by the mAb OKM5 and a goat antimouse F(ab′)2 (A) and P falciparum peptide PpMC-179 (C). The activation of CD36 both by cross-linking with antibodies (B) or the parasite peptide (D) was inhibited by the selective Src-family kinase inhibitor PP1 but not the inactive analog PP3. WB indicates Western blot. 1° and 2° refer to primary and secondary antibody, respectively.
