Gene structure, primer position, and RT-PCR results.

(A) Schematic representation of the API2 andMALT1 gene structure and primer position. Known breakpoints are indicated by arrowheads, and the nucleic acids are numbered according to the cDNA sequence of the API2 (GenBank no. NM001165) and MALT1 gene (GenBank no. AF130356). The incidences of these breakpoints were given in percentages. The position of primers used for frozen tissue are indicated by f-S and f-AS, whereas the position of primers used for fixed tissue are indicated by p-S, p-AS1, p-AS2, and p-AS3. (B) The upper panel shows the RT-PCR results from cases with frozen tissues. The lower panel displays the RT-PCR results from cases with fixed tissue. The numbers correspond to the case number in Table 1.