Effects of antithrombin (AT) and other materials on renal ischemia/reperfusion (I/R)–induced increases in serum levels of BUN and creatinine.

Serum levels of BUN (A) and creatinine (B) were determined 24 hours after reperfusion. mAT indicates Trp49-modified AT. Data are expressed as means ± SDs from 6 animals. *P < .01 versus sham-operated group; §P < .05 versus vehicle-treated group; †P < .01 versus AT-treated group; ¶P < .01 versus IM-treated group.