Changes in serum levels of blood urea nitrogen (BUN) and creatinine in rats after renal ischemia/reperfusion (I/R).

Serum levels of BUN (A) and creatinine (B) were measured before ischemia (Pre) and at 3, 6, 12, 24, and 48 hours after reperfusion. Data are expressed as mean ± SD values of 6 animals. Open circle indicates sham-operated group; filled circle, vehicle-treated group. *P < .01 versus the sham-operated group.