Fig. 4.
![Fig. 4. ITD mutations profoundly change gene expression profiles of myeloid progenitor cells. / (A) Scatter plot of the gene regulation values of IL-3 (ratio of IL-3 and medium [MED]) versus Flt3-ITD. (B) Scatter plot of the gene regulation values of ligand-activated Flt3-WT (ratio of FL and medium [MED]) versus Flt3-ITD. R depicts the correlation coefficient of logarithmically transformed expression ratios (Spearman nonparametric correlation).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/8/10.1182_blood-2002-06-1677/4/h80834133004.jpeg?Expires=1724243023&Signature=Vw0CkYE-9-waxXi2SN-YxaH5LNBtMeOsukTPtHv05Gn2BQogwErtSU6dSkqRsBsctlCLnjQWXE9tgoQdgecszYKO8vUf3HjOuYN9QY8iGJgV9Bks6uP93-r8Jt2No4zThROxx7vJL~yxws9ten8XbG8U-4ipMe3nTPs-CgJMuJ6pRJJs98LECRKD-y3zjDHQi3DFvdNvSb4VufV8zgn0mMun94S3ru-GPnUGRkBs3dgceCXCr8AkKk6KidYYpM3aKU8l~Rt54ArQVWmhGcM15~Ds4jDvB72MIe~6NJDy3CD1z1RoArz-f8xA2Mn2gOuMvFRL9UBdNcDDDvJL9QUVAQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
ITD mutations profoundly change gene expression profiles of myeloid progenitor cells.
(A) Scatter plot of the gene regulation values of IL-3 (ratio of IL-3 and medium [MED]) versus Flt3-ITD. (B) Scatter plot of the gene regulation values of ligand-activated Flt3-WT (ratio of FL and medium [MED]) versus Flt3-ITD. R depicts the correlation coefficient of logarithmically transformed expression ratios (Spearman nonparametric correlation).
