Fig. 7.
SAA induces Ca2+ mobilization through PFRL1/LXA4R in neutrophils.
Neutrophils labeled with Indo-1 were stimulated with SAA (1 μM), MMK-1 (10 nM), LXA4 (1.4 μM), and fMLF (10 nM) in different sequence combinations to determine cross-desensitization. Changes of intracellular Ca2+ are expressed as relative fluorescence ratio (405:485 nm). Results shown are representative of 1 of the 2 experiments.
