Fig. 4.
![Fig. 4. Distortion of thymic, splenic, and lymph node architecture by anti-CD45 treatment. / Samples of thymus, spleen, and lymph node collected on days 1 and 30 from untreated mice and from mice treated with anti-CD45 (1 μg/g body weight) were stained with antibodies against CD5 T cells (in the thymus and lymph nodes) and against B220 B cells (in the spleen). The marker-positive cells were brown diaminobenzidine [DAB] against the blue nuclear stain hematoxylin. Severe distortion of normal thymic, splenic, and lymph node histology, first seen on day 1, persisted through day 30 (magnification × 10).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/6/10.1182_blood-2002-08-2379/4/h80633997004.jpeg?Expires=1722799499&Signature=zCIIwvxPQPEx91g88SzRhXt5pFq6-h1gFGQCoAGDnAeMyaHOY5oRN4VlJXynrZgZmnaVhWHLvGv~d5lQN0jutomw34kzx75A-4lPV36CCZ3u4xYzX7hpyi30RZ68MkP-9bZliKAsViIMctlJ5Ks3dJZ1UV8Vdyd4fAWCP~IrFqnjtZQykUODt5qNgHHqhZlvIiXxtsVXfYCsphod8LisolsoAc6KHiS3m7YCAYML6tTOiHyUOQ-ldPfM7ap1yxvacK40lPLsaQTdoW7IOcr52dJgi2LUMxf37SUuyKNdN~jGinv9eNw6kRoueFl7~8Hrf8O6DxXWouaonqlHcAZrmA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Distortion of thymic, splenic, and lymph node architecture by anti-CD45 treatment.
Samples of thymus, spleen, and lymph node collected on days 1 and 30 from untreated mice and from mice treated with anti-CD45 (1 μg/g body weight) were stained with antibodies against CD5 T cells (in the thymus and lymph nodes) and against B220 B cells (in the spleen). The marker-positive cells were brown diaminobenzidine [DAB] against the blue nuclear stain hematoxylin. Severe distortion of normal thymic, splenic, and lymph node histology, first seen on day 1, persisted through day 30 (magnification × 10).
