Fig. 5.
AcSDKP-induced angiogenesis in Matrigel plugs.
Rats were injected subcutaneously with 0.5 mL Matrigel containing saline or AcSDKP. Matrigel plugs were removed after 7 days and processed for histology as described in “Materials and methods.” (A) A representative image of Matrigel plug sections containing saline or 10−7 M AcSDKP (original magnification × 10); arrows indicate newly formed vessels. (B) Vessel numbers were scored in 10 random fields (31.4 mm2 total) localized on the border of plugs. Data are the mean ± SEM of 3 individual experiments including 4 animals per condition in each experiment.
