Fig. 4.
Activation of T-cell clones by normal and Arg2150His I2144-T2161 peptides.
T-cell clones B3:6 (A), B10:4 (B), and D9:E9 (C) were incubated with LE2E9 loaded with normal (⋄) or Arg2150His (▪) I2144-T2161 peptide at the indicated concentrations. After 16 hours of incubation, IFN-γ was measured in cell culture supernatant. Results are expressed as mean of duplicates ± SD.