Fig. 2.
Induction of protective antitumor immunity is not affected by MHC class I expression in allogeneic tumor vaccine after repeated immunizations.
BALB/c mice were inoculated subcutaneously with 5 × 106irradiated wild-type (■) or class I–positive B78H1(○) cells and challenged 14 days after the last immunization with 5 × 104 live C26 tumor cells. Number of vaccination rounds is indicated. Control mice were challenged with C26 cells without previous immunization (▪). Ten mice were included in each group.