Fig. 2.
Fig. 2. Two-color FISH to interphase nuclei isolated from paraffin-embedded tissue for the detection of the MALT1translocation. / The orange PAC 117B5 (centromeric to MALT1) and green PAC 59N7 (telomeric to MALT1) show separate signals on interphases of a t(14;18)(q32;q21)+ hepatic MALT lymphoma, confirming MALT1 rearrangement (A). The same hybridization pattern is observed in a pulmonary t(11;18)(q21;q21)+ MALT lymphoma (B), whereas fusion signals are found in normal control nuclei (C).

Two-color FISH to interphase nuclei isolated from paraffin-embedded tissue for the detection of the MALT1translocation.

The orange PAC 117B5 (centromeric to MALT1) and green PAC 59N7 (telomeric to MALT1) show separate signals on interphases of a t(14;18)(q32;q21)+ hepatic MALT lymphoma, confirming MALT1 rearrangement (A). The same hybridization pattern is observed in a pulmonary t(11;18)(q21;q21)+ MALT lymphoma (B), whereas fusion signals are found in normal control nuclei (C).

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