Fig. 2.
Fig. 2. Functional FVIII expression kinetics in adult hemophilic FVIIIKO-SCID mice following HC-Ad gene transfer. / Mice were injected intravenously with Ad-AAT-cFVIII at a dose of 5 × 109 (A), 109 (B), 5 × 108 (C), 108 IU (D), and 5 × 107 IU (E) or with Ad-AAT-hFVIII at a dose of 5 × 109 IU (F). FVIII-deficient littermates were injected with PBS as control.

Functional FVIII expression kinetics in adult hemophilic FVIIIKO-SCID mice following HC-Ad gene transfer.

Mice were injected intravenously with Ad-AAT-cFVIII at a dose of 5 × 109 (A), 109 (B), 5 × 108 (C), 108 IU (D), and 5 × 107 IU (E) or with Ad-AAT-hFVIII at a dose of 5 × 109 IU (F). FVIII-deficient littermates were injected with PBS as control.

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