Fig. 2.
Correlation of basal O2− levels with IC50 of 2-ME in CLL cells.
Primary leukemia cells were isolated from 50 patients with CLL. The basal O2− levels and IC50 value of 2-ME in CLL cells was determined as described in “Materials and methods.” Linear regression analysis indicates that the basal O2− levels were significantly correlated with the IC50 values of 2-ME in CLL cells (P = .011).
