Models for the role of C/EBPα in hematopoietic differentiation and lineage commitment.

(A) Known effects of Id1 expression on erythroid differentiation and the complex of GATA-1, TAL1 (SCL), Lmo2, and Ldb1 are shown. (B) Different mechanisms of “direct” target gene activation/repression by C/EBPα (for review see Loken et al18).