RV cells are as efficient as PBLs in generating antiallogeneic-specific cytotoxic effectors.

PBLs (A) and RV cells (B) were stimulated against fully mismatched irradiated PBMCs. Cytolytic activity was measured in a cold inhibition cytotoxic assay at different E/T ratios against PHA-derived lymphocytes from the same targets (closed symbols). As negative control, cytolytic activity against autologous PHA-derived lymphocytes (open symbols) was measured. Results from 3 experiments are shown.