IL-10 and Th2 cytokines stimulate GILZ production by human monocytes.

(A) GILZ mRNA from monocytes cultured with or without IL-10, IL-4, or IL-13 was amplified by RT-PCR. Optical density of amplified product was determined, and each is expressed as the mean ± SEM of 3 experiments. (B) GILZ protein in Western blot studies with monocytes cultured alone or with IL-4, IL-10, or IL-13. Results from 1 experiment typical of 2.