HGAL mRNA expression is induced by IL-4.

Enriched peripheral blood B cells were untreated or stimulated with IL-4 (100 U/mL) or F(ab′)₂ antihuman μ antibodies (0.5 μg/mL) separately or in combination with CD40L for 6 and 24 hours (see “Patients, materials, and methods” for a detailed description of the processes). Results from 1 experiment representative of 4 are shown. HGAL expression was calculated as described in the legend to Figure 4 and in “Patients, materials, and methods.”