Contribution of Box E to the activity of theCD11c promoter in untreated hairy cells.

The luciferase reporter construct p11Wt, containing the wild-type CD11c promoter, was transfected in parallel with the Box E mutant p11ΔE into Mo, EH, and HK hairy cells. After correction for transfection efficiency, the level of expression of p11Wt is assigned a value of 100%, and the expression level conferred by p11ΔE is displayed as a proportion of this value. Each bar represents the mean ± the standard deviation of 3 independent transfection experiments.