The proximal promoter region of the CD11cgene drives transcription in hairy cells.

The expression construct p11Wt containing nucleotides − 128 to + 36 of the CD11c gene promoter was transfected into the cell lines Mo, EH, HK, and IM-9. Transfected cells were then left untreated for 16 hours prior to harvesting. The level of luciferasereporter gene activity, corrected for transfection efficiency, is expressed relative to that conferred by the negative control plasmid pATLuc. Each bar represents the mean ± the standard deviation of 3 independent experiments.