Fig. 1.
Fig. 1. CD13/APN induction is modulated by inhibitors of signaling intermediates. / KS1767 cells in 1% serum were incubated with (+) or without (−) bFGF and the indicated chemical inhibitors of signal transduction intermediates: PD98059, MEK inhibitor; wortmannin, PI-3K inhibitor; and manumycin A, Ras inhibitor. Total cellularCD13/APN mRNA or control 28S levels were assessed after 24 hours.

CD13/APN induction is modulated by inhibitors of signaling intermediates.

KS1767 cells in 1% serum were incubated with (+) or without (−) bFGF and the indicated chemical inhibitors of signal transduction intermediates: PD98059, MEK inhibitor; wortmannin, PI-3K inhibitor; and manumycin A, Ras inhibitor. Total cellularCD13/APN mRNA or control 28S levels were assessed after 24 hours.

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