Fig. 3.
Fig. 3. Correlation of bioluminescent signal intensity with tumor burden. / (A) Linear correlation (r = 0.989) between bioluminescent signal intensity determined in vivo and tumor burden as determined by FACS analysis of isolated cells from the liver and spleen of tumor-bearing animals (n = 15) 1 to 4 weeks after intravenous injection of 2 × 103 BCL1-gfp/luccells. (B) FACS plots represent analyses of the hematopoietic cell fraction (CD45+) of liver and spleen from an animal with high (▪ in panel A, top row) and one with low tumor load (▴ in panel A, lower row). Numbers represent the percentage of cells within quadrants.

Correlation of bioluminescent signal intensity with tumor burden.

(A) Linear correlation (r = 0.989) between bioluminescent signal intensity determined in vivo and tumor burden as determined by FACS analysis of isolated cells from the liver and spleen of tumor-bearing animals (n = 15) 1 to 4 weeks after intravenous injection of 2 × 103 BCL1-gfp/luccells. (B) FACS plots represent analyses of the hematopoietic cell fraction (CD45+) of liver and spleen from an animal with high (▪ in panel A, top row) and one with low tumor load (▴ in panel A, lower row). Numbers represent the percentage of cells within quadrants.

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