Overall survival (OS) and disease-free survival (DFS) curves based on bax/bcl-2 ratio levels within the int/fav and poor-risk cytogenetics subgroups.

(A) The significant difference between less than 0.3 and more than 0.3 bax/bcl-2 ratios was maintained within the int/fav cytogenetics class with regard to overall survival (P = .02). Within the poor-risk cytogenetics category, pts with lower bax/bcl-2 ratio levels showed a less favorable outcome than those with higher bax/bcl-2 levels with regard to OS (B) (P = .01) and DFS (C) (P = .004).