Down-regulation of basal p50-NFκB and C/EBP-β expression on activation of PPAR-α in vivo.

Wild-type (+/+) and PPAR-α (−/−) mice were fed normal chow or 0.2% (w/w) fenofibrate (FF)–containing chow for 17 days, and total liver extracts were analyzed for p50-NFκB and C/EBP-β by Western blotting. Levels of β-actin are shown for confirmation of equal loading.