Fig. 1.
![Fig. 1. Effect of ciprofibrate and Wy 14643 on CRP and fibrinogen expression in human hepatocytes stimulated by IL-1 and IL-6. / CRP (A) and fibrinogen (B) concentrations were measured in culture medium by ELISA and were expressed as means ± SDs. Human hepatocytes were isolated and treated for 16 hours with 250 μM ciprofibrate (CF), 250 μM Wy 14643 (WY), or vehicle (dimethyl sulfoxide [DMSO]; C) and subsequently were stimulated with 25 ng/mL IL-1 or IL-6 for an additional 24 hours. Results of 1 representative experiment of 3 experiments with different donors are shown. *P < .05 compared with control.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/101/2/10.1182_blood-2002-06-1762/4/h80233682001.jpeg?Expires=1723137374&Signature=YquIyPZn8NAHWmoWtvpED1yMU172jKWu6fy08GOQkEyTK15Wj6EINlTH13yN9SfTjVAdWO0yTiWoC1WAIj06kyLxT3B6PrWeMWPv8PenfGoHNxj~p0JemJPznNo~TlC-tULfF6DwHlAiXY9epewrq~cB8HwgWW2ddXHh1J-9KjTIc74plrHssWhOA4FR1L6~y6QLZMdYqHbjsbCzNzG3HsVt~ChQttXZbAZWkqooOAaNs~SOhIhlLVkpXuuknDypX0UrUzTx5K4Cw~PRPuG-EysfEeDrA9FKXptO0~9dC-cZFbG0G1J6~EbPVxsVYR1wIuFXdq6m5R1MWL4Swyq8NQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of ciprofibrate and Wy 14643 on CRP and fibrinogen expression in human hepatocytes stimulated by IL-1 and IL-6.
CRP (A) and fibrinogen (B) concentrations were measured in culture medium by ELISA and were expressed as means ± SDs. Human hepatocytes were isolated and treated for 16 hours with 250 μM ciprofibrate (CF), 250 μM Wy 14643 (WY), or vehicle (dimethyl sulfoxide [DMSO]; C) and subsequently were stimulated with 25 ng/mL IL-1 or IL-6 for an additional 24 hours. Results of 1 representative experiment of 3 experiments with different donors are shown. *P < .05 compared with control.
