Immunoreactivity of eotaxin in CTCL.

(A) Eotaxin/CCL11 immunoreactivity in cryosection of CD30⁻CTCL with the use of the alkaline phosphatase/anti–alkaline phosphatase method. Eotaxin/CCL11 is present only in connective tissue cells; tumor cell staining is negative. Original magnification, × 400. (B) Eotaxin/CCL11 immunoreactivity in cryostat section of CD30⁺ large-cell CTCL with the use of the alkaline phosphatase/anti–alkaline phosphatase method. Eotaxin/CCL11 is present in connective tissue cells and tumor cells, which were CD30⁺ in serial sections (data not shown). Original magnification, × 400.