Human CD34⁺ cells engrafted NOD/SCID/MPSVII mice at levels comparable with those of NOD/SCID mice.

NOD/SCID (N/S) and NOD/SCID/MPSVII (N/S/M) mice received transplants of human CD34⁺ cells from cord blood (CB) or mobilized peripheral blood (MPB) sources. The percentage of cells expressing human CD45 in the bone marrow of these mice was determined by flow cytometry 6 or 12 weeks following transplantation. Each dot represents data from a single mouse.