Analysis of TH phenotype from 2 different types of cutaneous lesion.
(A) Mean and SD from 3 separate DTH reactions as shown in Figure5. (B) Similar analysis of lymphocytes derived from biopsies of chancroid pustules from cutaneous H ducreyi infections of 3 individual patients. For each cutaneous lymphocyte donor, peripheral blood was compared with the database of 10 healthy donors presented in Figures 2 and 3. The composition of peripheral blood (for each subset shown in this figure) was not significantly different from this database using the Mann-Whitney rank-sum test (not shown). The difference between peripheral blood and skin-infiltrating cells was significant for the CD45RA− (P < .05), CLA+ (P < .05), and CCR4+(P < .05) populations. The difference between peripheral blood and skin-infiltrating cells was not significant for the CD27+/CCR7+, CD27−/CCR7−, or CCR10+populations.
