Fig. 7.
Fig. 7. CDC. / Lymphoma cells (A-D) or NT B cells (E) were incubated for 2 hours with 2 μg/mL rituximab in the presence of 30% human serum, and cell lysis was determined by PI incorporation (black bars). Gray bars represent relative CD20 expression. INH values (defined as the product of MFI values for CD46, CD55, CD59) are represented by white bars. (F) Correlation between CDC and CD20/INH. MFI values of CD20 were divided by INH values for each cell and plotted against CDC.

CDC.

Lymphoma cells (A-D) or NT B cells (E) were incubated for 2 hours with 2 μg/mL rituximab in the presence of 30% human serum, and cell lysis was determined by PI incorporation (black bars). Gray bars represent relative CD20 expression. INH values (defined as the product of MFI values for CD46, CD55, CD59) are represented by white bars. (F) Correlation between CDC and CD20/INH. MFI values of CD20 were divided by INH values for each cell and plotted against CDC.

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