Analysis of the expansion kinetics of B6^dom1-specific T cells and EL4 cells following adoptive T-cell transfer in B10 and B10.H7^b hosts.

BM cells (10⁷) and spleen cells (5 × 10⁷) from donors preimmunized with B10 splenocytes on day −14 were injected into irradiated (10 Gy) B10 or B10.H7^b recipients on day 0. Some groups were injected with 5 × 10⁵ EL4 cells on day +1 (+EL4). (A) Proportion and absolute number of EL4 cells found in recipient spleen and BM (2 tibiae and femurs). (B) Proportion and absolute number of B6^dom1-specific T cells in recipient spleen and BM. Results are depicted as the mean ± SD of 3 mice per group.