Increased collagen- or U46619-induced platelet ATP secretion with transgenic platelets.

(A) Parallel recordings of light transmission (%) and ATP secretion (μM) in WT or TG mouse hirudinized PRP during platelet stimulation with 0.5 μg/mL collagen. (B) Identical experiment after platelet stimulation with 4 μM U46619. Data are representative of at least 3 independent experiments performed in duplicate on platelets from WT and TG mice.