Fig. 3.
Effect of anti–MHC class I antibodies on LP-1 lysis.
Lysis of the myeloma cell line LP-1 by CTLs induced with LP-1 total RNA is blocked by anti–MHC class I antibodies. LP-1 cells were51Cr-labeled for 1 hour, washed, and then incubated for 30 minutes at 37°C with an anti–MHC class I antibody (clone W6/32) or with a mouse IgG isotype control antibody at a final concentration of 50 μg/mL and used as targets in a 51Cr-release assay.
